Kennedy’s disease, also known as spinal medullary myasthenia gravis, is a hereditary neurodegenerative disease that can be treated symptomatically and causally. 1. Symptomatic treatment: all patients can be given vitamin B, methylcobalamin and other nutritive neurological treatments. For painful spasms, magnesium, tizanidine, baclofen, gabapentin, sodium valproate, carbamazepine, etc. are available. If diabetes mellitus is present in the patient, it is treated according to the current principles of diagnosis and treatment. Androgen replacement therapy not only fails to relieve the symptoms of androgen insensitivity, but can lead to worsening of clinical symptoms. If gynecomastia is not responding to hormonal therapy, surgical excision may be considered. If the patient is malnourished due to dysphagia, percutaneous endoscopic gastrostomy is feasible. For a small percentage of patients with respiratory dysfunction, noninvasive positive-pressure mechanical ventilation can improve the patient’s symptoms. If patients with advanced respiratory failure, if necessary, according to the patient’s will to decide whether to perform mechanical assisted ventilation. 2. Causal treatment: Androgen inhibition therapy can be carried out. Leuprolide, as a luteinizing hormone-releasing hormone antagonist, can slow down the progress of the disease by inhibiting the production of testosterone and dihydrotestosterone. If you are diagnosed with Kennedy’s disease, please visit your doctor regularly and standardize your treatment under the guidance of a medical professional. The above medications and treatments should be administered under the guidance of a medical professional.