The time to apply leukapheresis varies from person to person due to the suppression of bone marrow hematopoiesis after the use of chemotherapeutic drugs. In some cases, the white blood cells may rise three to five days after the use of the drug, while some patients may need a longer period of time. Therefore, the application of leukocyte-boosting drugs should be checked regularly, according to the white blood cell count at any time to decide to reduce or stop the use of leukocyte-boosting drugs. Leukocyte-boosting drugs are recombinant human granulocyte colony-stimulating factors, which are mainly used for the treatment of leukopenia. Because leukemia patients need a large number of chemotherapy drugs, during which bone marrow suppression occurs, resulting in a decrease in the number of leukocytes in the peripheral blood, leukocyte-boosting injections are usually needed for treatment. The duration of leukapheresis varies from person to person. In some cases, the white blood cells may rebound in three to five days after the administration of the injection, while in other cases, it may take longer, and the exact duration of the injection should be determined by regular blood tests to check the number of white blood cells. Increase the dosage of leukocyte injection or stop using, need to regularly test the blood routine, need to strictly comply with the physician’s instructions, standardized use of drugs.