The pain under the nose when pressed may be caused by nasal boils, nasal vestibular cysts or trauma, and sinusitis is not excluded. 2. Nasal vestibular cyst: It may be related to the blockage of mucus ducts in the nasal vestibule, and the local secretions may be retained and cannot be discharged, causing painful symptoms under the nose when pressed. If the lower part of the nose is hit or squeezed, it may lead to local skin damage and pain when pressed, as well as redness; 4, sinusitis: if you suffer from sinusitis, cold air stimulation, allergies and other induced attacks, it can also be manifested as pain when pressed under the nose, often accompanied by nasal congestion, runny nose symptoms.