A splinter in the palm of the hand can be removed by softening the skin, picking it out with a sterile needle, or undergoing surgery. 1. Softening the skin: After the palm is impaled, the palm can be immersed in warm water. The hot water relaxes the superficial skin tissues and squeezes the surrounding skin so that the impingement comes out from the inner layers of the skin. 2. Sterile needle picking out: If there is still a residue in the skin of the palm of the hand, you can use a sterile needle to pick it out, or use tweezers to take it out. However, this should be done under the guidance of a doctor, and should not be done privately to avoid the possibility of local infection and damage to blood vessels and nerves. 3. Surgical removal: If the above methods still can not be removed, surgery can be performed under local anesthesia, cut the skin to find the splinter and then remove it, and pay attention to local cleanliness and hygiene after the operation, change the medication regularly, and prevent the wound from getting infected. If the palm of the hand into the thorn deeper, need to be injected with tetanus antitoxin to prevent tetanus, and take amoxicillin and other antibiotics to prevent infection.