The course of H. pylori treatment lasts about 14 days, and if the treatment fails, the medication needs to be adjusted to continue the treatment. H. pylori treatment, including triple therapy and quadruple therapy. We recommend quadruple therapy including proton pump inhibitor, bismuth, and two antibiotics, the course of treatment is about 10-14 days, twice a day, and treatment options such as omeprazole, bismuth potassium citrate, amoxicillin, and furazolidone. At the end of the treatment, carbon 13 or 14 needs to be rechecked after 4 weeks of complete drug cessation, and if the infection still exists, it needs to be eradicated again three months after the 1st eradication, and the dose and type of the drug should be adjusted according to the doctor’s prescription. If the condition is more serious and not sensitive to the treatment drugs, the treatment course may be prolonged. If Helicobacter pylori infection occurs, it is recommended to consult a doctor in time, under the guidance of the doctor for treatment to avoid further aggravation of the condition, the drug should be taken as prescribed by the doctor.