Sore nose and sneezing after waking up can be caused by allergic rhinitis, vasomotor rhinitis, cold and other diseases. 1. Allergic rhinitis: there may be dust, mites and other allergens in the indoor air, which cause irritation to the nasal cavity and then a stress reaction will occur, such as a sore nose, sneezing, runny nose and other manifestations. 2. Vasomotor rhinitis: often caused by autonomic nervous system dysfunction, itchy nose, nasal congestion and runny nose often occur after alternating hot and cold, exercise and diet. 3. Cold and flu: If you do not take proper measures to keep warm when you go to bed at night, resulting in cold and wind, it is likely to induce cold and flu, which will lead to the symptoms of soreness of the nose and sneezing after waking up. When the symptoms worsen, headache, fatigue, fever and other systemic manifestations. There are many reasons for waking up with a sore nose and sneezing, so it is recommended to consult a doctor for a clear diagnosis and symptomatic treatment.