Cardiovascular complications (coronary heart disease, stroke, peripheral vascular disease) are important complications of diabetes. It is the most important cause of death in patients with type 2 diabetes. Cardiovascular disease has received much attention. However, little attention has been paid to the offspring of diabetic patients, and prevention and treatment of this group has been neglected. It is well known that diabetes runs in families. Many children of diabetic patients pay great attention to the prevention of diabetes. However, the prevention of cardiovascular disease has been neglected. It is well documented that vascular complications appear before the onset of diabetes and that 50% of newly diagnosed type 2 diabetics already have macrovascular disease. Vascular endothelial dysfunction is an early reversible pathological process that precedes the onset of clinical cardiovascular disease and is the pathological basis of vascular disease, and if treated effectively at this stage. It will delay the onset of vascular disease. We measured the endothelium-dependent vasodilatory function of the brachial artery in children with type 2 diabetes mellitus with normal glucose metabolism (currently the best method to study vascular endothelial function) by two-dimensional ultrasound. When compared with healthy individuals of similar age, endothelium-dependent vasodilatory function was found to be significantly lower in children of diabetic patients than in healthy individuals; their blood tests also revealed that. Their lipid levels and insulin levels were higher than those of healthy individuals. Some inflammatory factors closely related to cardiovascular disease (e.g., endothelin, plasma fibrinogen activator inhibitor 1, serum soluble vascular cell adhesion molecule 1, VW F, C-reactive protein) were elevated. Some genes related to vascular endothelial function (e.g., endothelial-type nitric oxide synthase gene) are altered with genetic polymorphisms. Vascular endothelial function is closely related to blood lipids, insulin sensitivity, inflammatory factors, and is also associated with obesity. It can be inferred from these findings . Children of diabetic patients are already at risk of developing diabetes and cardiovascular disease, although they do not yet have diabetes. Therefore. Children of diabetic patients should take some strong measures. To delay the occurrence of diabetes and cardiovascular disease as much as possible. Foreign scholars found that after a 2-year study on children of diabetic patients. Change their lifestyles. Increase the amount of exercise. Improved dietary structure led to a decrease in their lipid levels (lipids are also an important factor affecting vascular endothelial function and often co-exist with diabetes) and an increase in insulin sensitivity. This suggests that. Through lifestyle changes and increased exercise. The onset of diabetes and cardiovascular complications can be delayed. The following are some specific measures to prevent diabetes and cardiovascular complications: First, we should change our unhealthy lifestyle and maintain an optimistic and open-minded attitude towards life. Try to participate in physical exercise as much as possible. Promote aerobic metabolic exercise, such as walking, running, cycling, etc.; improve the structure of the diet, including low sugar, low salt, low fat, low cholesterol, high fiber, vitamin-rich diet, avoid excessive eating; do not drink too much alcohol, because alcohol can provide too much heat, too much will also increase the burden on the liver, increase blood lipid levels and thus affect insulin sensitivity and vascular endothelial function. Second, quit smoking. Even for healthy people, smoking can cause changes in vascular endothelial function and induce cardiovascular disease, and is more harmful to children of diabetics with a genetic predisposition to diabetes. Third. Monitor your weight frequently and measure your abdominal circumference. People who are overweight or whose abdominal circumference exceeds the prescribed standard should take timely weight loss measures, because obesity is more likely to cause insulin resistance and changes in vascular endothelial function, which can lead to diabetes and cardiovascular disease. Fourth. To regularly check the blood lipid situation. If there is an increase in cholesterol, triglycerides and LDL and a decrease in HDL, it is important to contact your doctor. Take oral lipid-lowering medications. Try to avoid damage to vascular endothelial function caused by elevated blood lipids. Fifth. Monitor blood pressure regularly. Because children of diabetic patients are more likely to have elevated blood pressure. Increases the chance of vascular disease.