There are many diseases that cause acromioclavicular pain, such as acromioclavicular fracture, rotator cuff injury, and biceps long head tendonitis. Clinical treatments include general treatment, drug treatment and surgical treatment according to the specific cause of the disease. 1. Fracture of the acromion: It is a kind of rare fracture in clinic, which can be caused by direct violence or indirect violence and other factors. Clinical treatments mainly include manipulative reduction treatment, surgical treatment, etc. If manipulative reduction fails, open reduction combined with internal fixation can be used for surgical treatment. 2. Rotator cuff injury: it is a kind of disease causing shoulder joint dysfunction, mostly caused by trauma or repeated exercise. Clinical treatment mainly includes general treatment, medication and surgery. Patients need to pay attention to rest and avoid overwork; they can take diclofenac and celecoxib as prescribed by doctors for pain relief; if necessary, they can choose arthroscopic surgery and other surgical treatments. 3. Biceps long head tendonitis: it is a disease caused by inflammation of part of the tendon sheath, which can be related to trauma, chronic strain and other factors. Clinical treatment mainly includes general treatment, drug treatment, physical therapy and so on. Patients need to pay attention to rest, avoid overwork; can follow the doctor’s instructions to take aspirin, ibuprofen and other drugs anti-inflammatory analgesic; if necessary to take short-wave therapy, intermediate frequency therapy and other physical therapy to relieve pain. If the pain in the acromion is persistent and cannot be relieved, the patient should go to the hospital immediately and undergo the relevant examination in order to clarify the cause of the disease and actively cooperate with the doctor’s treatment.