Cephalosporin II belongs to the cephalosporin class of antibiotics, which mainly treats bacterial infections, but can only target infections caused by antibiotic-sensitive bacteria. Cephalosporin II is not effective if it is resistant to Cephalosporin II. Cephalosporins of the second generation are able to treat infections caused by gram-negative bacteria and are also moderately effective against gram-positive bacteria. Compared with the first generation cephalosporins, the antibacterial activity of the second generation cephalosporins against gram-positive bacteria is slightly weaker, but the antibacterial activity against gram-negative bacteria is stronger. Gram-negative bacteria such as Klebsiella, Escherichia coli, Enterobacter cloacae, Shigella dysenteriae, the effect of second-generation cephalosporins is okay, but the effect on Pseudomonas aeruginosa is poor. It should be noted that the second generation cephalosporins still have some nephrotoxicity, but it is lower than the first generation cephalosporins.