After a patient is in a coma, the physician needs to objectively examine the patient and give the corresponding auxiliary examination. This is also the point of differentiation between moderate and deep coma. 1. External stimulus response: when the patient is in moderate coma, he or she does not respond to the surrounding things and various external stimuli, and may have defense reflexes for strong stimuli; when the patient is in deep coma, the whole body When the patient is in deep coma, the whole body is relaxed and does not respond to various external stimuli; 2. Reflex reaction: when the patient is in moderate coma, the corneal reflex is weakened and the pupil-to-light reflex is not sensitive, but the eyes turn with both sides when the head is turned; when the patient is in deep coma, the tendon reflex, cough reflex, swallowing reflex, corneal reflex and pupil-to-light reflex are all gone; 3. When the patient is in deep coma, the vital signs are unstable, such as irregular respiration, decreased blood pressure, urinary and fecal incontinence, retention, etc.