Sleeping with eyes half-open and half-closed refers to incomplete eyelid closure, which may be caused by physiological phenomenon, hyperthyroidism, facial nerve palsy, etc. Patients can be treated by general treatment, medication, surgery, etc., and the specific treatment is related to the cause of the patient’s illness. 1. Physiological phenomenon: some people may have incomplete eyelid closure during sleep, resulting in half-open and half-closed eyes, but the cornea is usually not exposed and does not come with any symptoms, which is a normal physiological phenomenon and does not require special treatment. 2. Hyperthyroidism: Patients with hyperthyroidism may have protruding eyeballs, leading to half-open and half-closed eyes during sleep. Patients can follow the doctor’s instructions to treat hyperthyroidism, such as oral methylthiouracil, etc., to relieve eye discomfort. For patients with prominent eyeballs, surgical treatment, such as intraorbital decompression surgery, is possible. 3. Facial nerve palsy: Facial nerve palsy patients due to paralysis of the orbicularis oculi muscle, eyelid skin relaxation and ptosis can occur, which will lead to the patient sleep, the eyes are half-open and half-closed performance. It is recommended that patients with incomplete eyelid closure and other discomforts consult a doctor to evaluate their condition and follow the doctor’s instructions for treatment.