The cause of Turner syndrome is mainly related to genetic aberrations. In a normal woman, her chromosomes should be 46,xx, but in a patient with Turner syndrome, most of her chromosomes are 45,x0, and in a few cases, they are chimeric, 45,x0,46,xx at the same time, which means that the X chromosome is missing from the sex chromosomes in the patient. There may be a relationship with the non-segregation of the sex chromosomes in the father’s cells. To prevent Turner syndrome, it is important to take folic acid supplements during pregnancy and during pregnancy preparation. Do maternity checkups on time to confirm whether the fetus has serious congenital defects through prenatal screening and prenatal diagnosis; early detection and early intervention can reduce the birth of defective babies. Timely screening and treatment of the disease after birth can prevent or reduce the disease and improve the quality of life of children with the disease. The main cause of Turner syndrome is genetic abnormality, and screening during pregnancy is especially important to detect and intervene early to reduce the birth of defective babies.