Amikacin is an antibiotic of the aminoglycoside class and can be used to treat tuberculosis. However, it is commonly used as adjuvant therapy in clinical practice, and the preferred first-line drugs used in clinical practice for the treatment of tuberculosis are isoniazid, rifampicin, ethambutol, pyrazinamide, streptomycin, and so on. When the body can not tolerate the treatment of streptomycin or patients with allergic reactions to streptomycin, amikacin can be used instead. Amikacin is very active in killing Mycobacterium tuberculosis and has a lower relative toxicity than streptomycin. In the process of treating tuberculosis with amikacin, it is necessary to pay attention to the review of liver and kidney function to prevent liver and kidney damage, and adjust the treatment program at any time.