For chronic urticaria you can use topical hormones, antibiotics or antifungals. 1. Weak-acting hormones, such as hydrocortisone butyrate and dronedar, can be used in the folds of the head, face and perineum. Medium-acting hormones, such as mometasone furoate, can be used on the palms of the hands, palmoplantar areas, and trunk areas of the body. 2. Chronic urticaria can be treated with antibiotics such as erythromycin ointment, mupirocin and polymyxin B if bacterial infections occur as a result of frequent scratching. 3. Trimethoprim is an antifungal compound that can effectively relieve allergies in folded areas, thin and tender areas, skin areas, and can be used on the head and face. It is recommended to use the drug under the guidance of a doctor to avoid adverse reactions caused by indiscriminate use of drugs.