The swelling and pain on both sides of female vulvar lips are considered to be related to vulvitis, vestibular gland abscess, local hematoma, etc. The treatment should be based on the cause of the disease and choose general treatment, drug treatment, surgical treatment and other ways of treatment. 1. Vulvovaginitis: for the combination of vaginitis or body resistance is relatively low, the local tissue is stimulated by abnormal secretions or bacterial infection caused by local tissue congestion and edema vulvovaginitis, the patient will appear vulvovaginal lips on both sides of the swelling and pain and other discomforts, at this time can be used in accordance with the doctor’s instructions for the use of bifidobacterium suppositories vaginal topical application or the use of erythromycin ointment topical application, during the period of treatment, to keep the vulva dry and clean, and eat a light diet. 2. Vestibular gland abscess: If the ductal opening of the vestibular gland is blocked and a retention cyst is formed locally, combined with bacterial infection, it will lead to the occurrence of vestibular gland abscess, due to the obvious redness and congestion of the local tissues and the increase of the tension, the patient can show obvious swelling and pain, 1:5000 potassium permanganate solution can be used for sitz baths, and the patient should follow the doctor’s advice to be operated through surgery in time for incision and drainage if necessary. 3. Local hematoma: because the labia majora tissue is relatively loose, and the local blood vessels are rich, so the vulva is easy to form labia majora hematoma after trauma and manifested as local swelling and pain, if the bleeding is not much, no special treatment; if the hematoma is obvious, follow the doctor’s instructions to use Yunnan Baiyao to stop the bleeding, and promote the absorption of the local hematoma with physiotherapy if necessary. For women with swelling and pain on both sides of the labia majora, it is recommended that they go to the gynecology department of a regular hospital, complete gynecological examinations, leukorrhea, blood tests and other related examinations, and then take active treatment under the guidance of the doctor after clarifying the cause of the disease.