Non-atrophic gastritis with bile reflux generally does not matter, but requires prompt treatment as prescribed by the doctor. If bile reflux occurs in non-atrophic gastritis, the gastric mucosa may be damaged and the intrinsic glands of the gastric mucosa may atrophy, further aggravating the condition. If left untreated, complications such as anemia, gastrointestinal bleeding, and malnutrition may occur and may develop into atrophic gastritis. Non-atrophic gastritis requires the use of drugs that inhibit gastric acid, such as omeprazole and ranitidine, as well as drugs that protect the gastric mucosa, such as Rebapatide and bismuth pectin. Patients with bile reflux also need to use drugs that bind bile acids, such as magnesium aluminate preparations. In addition, if Helicobacter pylori infection is present, antibiotics such as amoxicillin and metronidazole should be used in combination to eradicate H. pylori and promote disease recovery. Therefore, patients with non-atrophic gastritis need to go to the hospital in time to improve the relevant examination and carry out scientific and standardized treatment. Be sure to use specific drugs under the guidance of a professional doctor and according to their own situation, so as not to aggravate the condition and affect the recovery.