There are some risks associated with having an amniocentesis, but nowadays it is done under the guidance of an ultrasound and the incidence of risk is low. Amniocentesis is an invasive procedure that carries some risks. As puncture may cause leakage of amniotic fluid or even contractions, which may trigger premature rupture of membranes, it may also cause bacterial infection of the amniotic cavity, which in turn may trigger miscarriage. Although there are certain risks in performing amniocentesis, it is now done under the guidance of ultrasound and the incidence of risk is low. If an abnormal chromosome number is detected during pregnancy, or if a pregnant woman is over 35 years of age and has a medical need for amniocentesis, she must not be put off because of the risks involved. For patients who need amniocentesis, cooperate with the doctor during the procedure, pay attention to rest and care after the procedure, and if symptoms such as abdominal pain, abdominal distension, or vaginal discharge occur, they should go to the hospital for examination in a timely manner in order to avoid adverse consequences.