Empty nails can be caused by fungal infection, nail trauma and chemical factors, which need to be treated reasonably after the cause is clearly identified. 1. Fungal infection: after clear diagnosis, it can be treated with reasonable medication, such as oral itraconazole, terbinafine, or topical application of amorolfine. 2. Nail trauma: If the nail is crushed or hit by heavy objects, resulting in separation of the nail plate from the nail bed, if it is not serious, you can wait for new nails to grow on their own, but if there is serious bruising or swelling, it is necessary to extract the nail if necessary. 3. Chemical factors: special occupational groups, nails for a long time by chemical substances, will cause nail peeling, manifested as nail separation syndrome, the most important thing is to stay away from the causative factors. If the nails appear to become empty, it is recommended to consult a doctor in a timely manner, after a clear diagnosis and then symptomatic treatment. The above medications should be used in accordance with medical advice.