Difficulty in defecation should seek medical advice to clarify the cause of the problem. If the cause is functional constipation caused by poor dietary structure and habits, enema treatment under the guidance of the doctor is the fastest way to solve the problem. In addition, following the doctor’s instructions to use the open plug or oral lactulose solution can also help to defecate as soon as possible. Constipation caused by colon cancer, intestinal polyps and other diseases should be actively treated. 1. Enema treatment: Patients who are evaluated to have no contraindication to enema can receive enema treatment in regular hospitals. The enema liquid will be passed into the anus, and defecation will be possible after 5~10 hours, which is one of the effective methods to solve the problem of defecation. 2. Keserol: colorless syrupy solution, under the guidance of a doctor, open the lid of the container, apply a little grease slowly inserted into the anus will be squeezed into the rectum, can lubricate the intestinal tract, rapid laxative. Adverse reactions are not clear, allergic to Keflex is prohibited. 3. Lactulose oral solution: yellow clear viscous liquid, oral treatment as prescribed by the doctor, can stimulate intestinal peristalsis, to ensure smooth stool. After use may have a slight nausea and other adverse reactions, galactose intolerance should not be used; diabetic patients, women in pregnancy, allergic to the drug, appendicitis, intestinal obstruction, abdominal pain is not known to be prohibited. 4. If the difficulty in defecation is caused by colon cancer, intestinal polyps and other diseases, active treatment of the original disease will help relieve the difficulty in defecation. It is suggested that patients should develop good dietary habits, consume less spicy, cold and greasy food, and take care of water supplementation to avoid defecation difficulties caused by dry stools. The medication should be used according to the doctor’s prescription.