Getting up in the morning with shoulder pain is considered to be cervical and shoulder myofasciitis, frozen shoulder, cervical spondylosis and so on. In addition, there are physiological reasons, such as shoulder pain caused by cold in the middle of the night. 1. Neck and shoulder myofasciitis: If the neck and shoulder area has been traumatized before, or often do some heavy physical labor, it will lead to aseptic inflammation of the fascia of the neck and shoulder area, which is mainly manifested as pain and discomfort in the neck, shoulder, back, etc. Generally in the morning after waking up or when the weather changes significantly, the symptoms aggravate and the pain will be alleviated after slight activities. 2. Frozen shoulder: Frozen shoulder is common in middle-aged and old people around 50 years old, it is a sterile inflammation of shoulder joint tissues, the main symptom is pain in the shoulder joint area, and the pain will be more serious after catching a cold. 3. Cervical spondylosis: cervical spondylosis and cervical spine degenerative disease, on the basis of degeneration, long-term strain will make the cervical spinal cord and nerve root compression caused by cervical spondylosis, the main symptom is the pain in the neck and shoulder, and the pain will radiate to the upper limbs. 4. Physiological reasons: There are also physiological reasons, such as pain caused by cold shoulder in the middle of the night. After warmth, exercise can generally relieve the pain. Shoulder pain in the morning may be due to other reasons, you should consult a doctor in time to clarify the cause and standardize the treatment.