Thyroid nodule swelling and pain, usually seen in subacute thyroiditis or thyroid nodule intracapsular hemorrhage, etc., the two treatments are different, the former is a self-limiting disease, the latter if the bleeding is large, need to rescue treatment in a timely manner, the details are described below. 1. Subacute thyroiditis: It is a granulomatous inflammation and is a self-limiting disease. Mild cases can be treated without medication, and if the neck is painful, non-steroidal anti-inflammatory drugs such as ibuprofen can be taken. 2. Thyroid nodule intracapsular hemorrhage: Its clinical manifestations are somewhat similar to those of subacute thyroiditis, but there is a process of rapid enlargement of the nodule. If thyroid nodule intracapsular hemorrhage has compression symptoms such as dyspnea requiring active resuscitation, it can be seen in the emergency department. Therefore, the swelling and pain of thyroid nodules should be treated differently depending on the cause of the disease, and it is recommended to consult a doctor for specific treatment.