The dna4.1E+5 is the hepatitis B virus DNA 4.1*10^5IU/ml, indicating active viral replication. Hepatitis B virus DNA is the core component of the virus, a sign of viral replication and infectiousness, and the most direct, specific and sensitive indicator of viral infection. Hepatitis B virus carriers who are positive for hepatitis B DNA for a long period of time are prone to recurrent liver function abnormalities, developing towards cirrhosis and liver cancer, with poor prognosis, and generally require antiviral treatment. Hepatitis B DNA positive, if there is abnormal liver function or liver histologic damage, need to take antiviral drugs to control viral replication. Currently, the commonly used antiviral drugs are entecavir and tenofovir, etc. Common adverse effects include fatigue, dizziness, nausea and abdominal pain. Antiviral drugs need to be taken under the guidance of a medical professional and should not be discontinued arbitrarily as sudden stopping of the drugs may lead to exacerbation of hepatitis.