Heat rash in the neonatal period can be treated with general therapy and medication to relieve or improve the symptoms. 1. General treatment: you can cool down and dehumidify, moderately reduce the temperature of the living environment, such as summer and fall, high temperature and humidity season, pay attention to cooling, indoor temperature to maintain at 22 ~ 26 ℃ is more appropriate. At the same time, attention should be paid to the care of newborns, pay attention to cooling in summer, try to use breathable, soft blankets, and keep clean. 2. Medication: external cooling and itching agent is a common treatment for prickly heat, with the role of itching, skin protection. Such as glycerin lotion. If for red prickly heat, can be local short-term use of glucocorticoid cream, such as hydrocortisone, Dinaid cream, etc., can significantly reduce itching, control inflammation, should pay attention to the use of serious symptoms, and non-routine treatment. Newborns with heat rash is recommended to go to the hospital in a timely manner, under the guidance of the doctor to carry out active treatment, do not unauthorized use of drugs to avoid adverse consequences.