Vibrio marine trauma is the predominant marine organism infection in the tropics and is commonly seen in elderly patients or those with underlying medical conditions. Vibrio maritimus infections present as skin lesions from marine shells, crabs, or fish without wounds, followed by widespread skin infections such as redness, swelling, and blistering within a short period of time, resulting in a systemic inflammatory response syndrome. Older patients may go into shock immediately after infection, and the early stage is to apply broad-spectrum antibiotics for anti-infective treatment. If the limb infection is severe, patients are advised to undergo surgical amputation to preserve the function or life of other organs. If there is a wound soaked in seawater or after being stabbed by fish, shrimp or shells, a skin wound breaks down and infection worsens within a short period of time, it is important to go to the hospital promptly because this infection is very dangerous and can easily be fatal.