Irritant cough usually needs to be treated for the cause, such as bacterial pneumonia, tuberculosis, lung cancer, cough variant asthma or other causes of irritant cough, which may require anti-infective, anti-tuberculosis, anti-tumor and other related therapeutic measures. 1. Bacterial pneumonia: the condition may require treatment with antibiotic drugs such as moxifloxacin and amoxicillin-clavulanate potassium. 2. Tuberculosis: cough caused by tuberculosis needs to be treated with anti-tuberculosis drugs such as rifampicin and ethambutol. 3. Lung cancer: Lung cancer is a kind of malignant tumor, which may need surgery-based comprehensive treatment. 4. Cough variant asthma: if this is the case, drugs such as budesonide formoterol may need to be inhaled. 5. Other causes: For example, cough caused by gastroesophageal reflux disease usually requires treatment with proton pump inhibitors such as rabeprazole and lansoprazole. Nasal secretion reflux stimulates coughing. Antihistamines (e.g., loratadine) and nasal mucosal constrictors (e.g., pseudoephedrine) can be applied to reduce secretion. Side effects of medications (e.g., captopril, etc.) can also cause irritant cough, and the regimen should be adjusted promptly in severe cases. In conclusion, irritating cough requires prompt medical attention to identify the cause, targeted treatment, as well as symptomatic measures to alleviate symptoms.