Zhi Bai Di Huang Wan and Pai Zi Yang Xin Wan are different in terms of drug composition and efficacy. Zhi Bai Di Huang Wan is composed of Zhi Mu, Huang Bai, Shu Di Huang, Cornu Cervi and other medicines, with the effect of nourishing yin and lowering fire (nourishing yin essence and lowering fire). It is used for the treatment of yin deficiency and fire exuberance (deficiency of yin essence in the body, resulting in hyperactive fire), hot flashes and night sweating (abnormal sweating after going to sleep, but sweating stops after waking up), dry mouth and sore throat, tinnitus, spermatorrhea, and short and yellowish urine. Pachyderm Pill is composed of Pachyderm, Radix Codonopsis, Radix Astragali, Rhizoma Ligustici Chuanxiong and other medicines, which has the effects of tonifying Qi, nourishing blood and tranquilizing the mind, and is used in the treatment of deficiency and coldness of heart qi, panic and heartbeat, insomnia and excessive sleepiness, and forgetfulness easily, and so on. The adverse reactions and contraindications of the two drugs are not clear. Zhi Bai Di Huang Wan and Pai Zi Yang Xin Wan should be used under the guidance of a professional doctor, and should not be used blindly on their own, so as not to aggravate the condition or produce adverse reactions.