The best results can be achieved by choosing targeted drugs for the treatment of different pathogenic microorganisms. 1. acute gonococcal urethritis caused by gonococcal infection, commonly known as gonorrhea, is best treated with cephalosporins; 2. non-gonococcal urethritis caused by chlamydia and mycoplasma infection is best treated with levofloxacin, clarithromycin, azithromycin and doxycycline; 3. The most effective treatment is to use levofloxacin, clarithromycin, azithromycin, doxycycline, etc.; 3, male UTI caused by mycobacterial infection, use itraconazole and other treatment; 4, for trichomonas infection caused by UTI, use metronidazole, tinidazole treatment is the best effect.