A. Surgical treatment methods for Parkinson’s disease? 1.Destructive surgery: Due to serious adverse effects, this approach has been basically no longer used in developed countries. 2, DBS surgery (deep brain electrical stimulation therapy): the best surgical treatment for Parkinson’s at present. Wang Hongwei, Department of Neurosurgery, Affiliated Hospital of Inner Mongolia Medical University 3, stem cell transplantation: It is still in the experimental stage, and the efficacy is not yet clear. What is DBS surgery (deep brain electrical stimulation therapy)? Deep brain electrical stimulation therapy uses electrodes implanted in the brain to send electrical stimulation to suppress abnormal brain nerve signals. The stimulation is delivered to precise targets related to motor control. The therapy allows Parkinson’s patients to normalize their motor functions, reduce their symptoms and improve their quality of life. Third, how effective is DBS in treating Parkinson’s disease? Clinical studies have shown that DBS for Parkinson’s disease has significant therapeutic effects: (1) it improves patients’ symptoms such as tremor, rigidity, slow or inability to move, and balance disorders; (2) it reduces the dose of oral medication; and (3) it significantly improves patients’ quality of daily life and ability. Experience shows that the effect is significant in patients who respond well to levodopa. IV. What kind of patients are suitable for DBS surgery? Patients who are clearly diagnosed with primary Parkinson’s disease 2. Patients who had good efficacy on levodopa, but now the efficacy of the drug has gradually decreased or side effects have appeared, and the disease has started to affect normal work and life 3. Patients who have no obvious intellectual impairment and are willing and able to cooperate during the surgery and subsequent follow-up 5. Contraindications and risks of DBS surgery? DBS is a kind of surgery, so all patients with contraindications to surgery are not suitable for the surgery, DBS has certain surgical complications like other brain surgeries, but as long as the surgical indications are chosen appropriately, the incidence of surgical complications is low. VI. Postoperative follow-up of DBS? Since Parkinson’s is a progressive disease, it is very important to follow up after DBS implantation by adjusting the stimulation frequency, pulse width, and voltage to achieve the best disease control and the least side effects. Follow-up visits are conducted 1-3 times a year for modulation testing. VII. What is the approximate cost of treatment? Usually 100,000 for unilateral and 200,000 for bilateral. There are 2 types of stimulators, domestic and imported.