Compression of the trigeminal nerve by a brainstem cyst can cause recurrent episodes of electric shock or knife-like sharp pain in the area of the trigeminal nerve distribution. Secondary trigeminal neuralgia caused by compression of the trigeminal nerve by a brainstem cyst can be treated with pain medication, surgery, and closed treatment. 1. Pain medication: For secondary trigeminal neuralgia caused by brainstem cysts, drugs such as carbamazepine and phenytoin sodium can be taken to relieve pain. Adverse effects of these drugs include dizziness, vomiting, unsteady walking, etc. The medication needs to be monitored regularly. 2. Surgery: Trigeminal neuralgia is caused by the compression of brainstem cysts, so surgical treatment to remove or reduce the size of the cysts and relieve the compression can effectively relieve the symptoms of trigeminal neuralgia. However, due to the importance of brainstem function, the surgical treatment of brainstem cysts is more difficult and the indications are more strict. 3. Closure therapy: if the effect of medication is poor and surgery is not possible, anhydrous ethanol or glycerin can be used to seal the trigeminal nerve branches or ganglia, so as to destroy the sensory cells in the distribution area of the trigeminal nerve, thus relieving the pain. In summary, when brainstem cysts compress the trigeminal nerve, in addition to the manifestation of trigeminal neuralgia, it can also be accompanied by symptoms such as facial sensory disorders and paralysis of masticatory muscles. If related discomfort occurs, it is recommended to consult a doctor in time in order to receive treatment.