Risks and accidents exist everywhere after cranial defects, and damage to the skull can occur when the skull is subjected to force majeure from the outside world, and cranial defects are one of the more common disorders in neurosurgery. For example, traffic accidents, production safety accidents, falling objects, fights, cranio-cerebral surgery, etc. may damage the skull and eventually cause skull defects. This requires prompt skull repair surgery, although some patients may still have a sense of entitlement. It is recommended to repair the skull if the defect is more than 3cm in diameter. If you don’t have the surgery in time, one of the reasons is that it will have a great impact on the beauty of the appearance, in addition to the lack of a part of the skull, the intracranial environment will change drastically, the intracranial pressure is unstable, the cerebrospinal fluid circulation in the skull and the cerebral blood circulation may be affected, and the neurological function of the cranium may be impaired, which may produce a series of cranial defect syndrome, affecting the physical and mental health of the entire human body. Another important point is the safety issue, if the head is not repaired in time, if the head is injured again, it may directly injure the brain tissue, and in serious cases, it may even directly endanger the life, which is very dangerous. Therefore, it is very necessary to have a skull repair surgery in time. The repair material is very important for cranial bone repair surgery, and the surgical technique is also very important. Currently, our team is carrying out PEEK cranioplasty, and has achieved good clinical results. We suggest that patients with skull defects should go to the hospital as soon as possible to choose the appropriate material to repair their skulls and regain their health as soon as possible.