There is no clear conclusion on the survival time of chronic obstructive pulmonary disease (COPD) to Stage IV. The specific survival time is related to many factors, such as the patient’s age, the aggressiveness of the treatment, whether there are other related diseases, etc. If the patient’s general condition is better and the treatment is active, the survival time may reach the natural life expectancy of a normal person; however, if the general condition is worse and the treatment is inactive, the survival time can be greatly shortened, and it may be ranging from a few months to a few years. Stage IV is the most serious period of chronic obstructive pulmonary disease (COPD), which is called extremely severe COPD. In Stage IV, the patient will experience obvious breathlessness, severe obstruction of daily activities, obvious chest tightness and shortness of breath even when washing his face or going to the toilet, as well as systemic symptoms. If the patient is relatively young and actively treated, and there are no other related diseases, the survival time may reach the natural life expectancy of a normal person. Daily should pay attention to quit smoking and alcohol, light diet, avoid spicy stimulating food, eat more fresh vegetables and fruits, improve immunity. If the patient long-term joint inhalation of hormones plus long-acting bronchodilators, attention should be paid to rinse the mouth in a timely manner after inhalation to prevent Candida albicans infection in the mouth. If the patient is older, or if the treatment is untimely and there are other related diseases, the survival time is shorter, which may range from a few months to a few years. In addition, another relapse of the disease can worsen the condition and even death can occur. Patients with chronic obstructive pulmonary disease are advised to consult a doctor in a timely manner and follow the doctor’s instructions for active treatment, which can effectively slow down the progression of the disease and greatly improve the patient’s survival.