The normal value of indirect bilirubin is 0 to 12 umol/L. 38 umol/L is higher than normal, and the determination of severity depends on the nature of the disease, which is still numerically mildly elevated.
When red blood cell destruction exceeds the metabolic capacity of the liver, indirect bilirubin is not glucuronidated in the liver, resulting in high indirect bilirubin. Physiological causes can be seen, but also pathological causes, common liver disease, hemolytic disease.
1. Physiological causes: newborn babies may have physiological jaundice resulting in elevated indirect bilirubin, which usually subsides within 2 weeks and does not require treatment.
2. Liver diseases: cirrhosis, viral hepatitis, severe fatty liver, etc. These patients have different degrees of liver damage, and there are different degrees of obstacles to bilirubin binding, excretion and uptake, resulting in high indirect bilirubin.
3. Hemolytic diseases: autoimmune hemolytic anemia, etc. These patients have a large number of red blood cells destroyed, thus forming a very large amount of indirect bilirubin, which exceeds the limit of liver uptake and binding, and eventually leads to high indirect bilirubin.
Indirect bilirubin 38μmol / L should be promptly to the hospital, improve the examination of the current cause, under the guidance of the doctor treatment.