Depression as a common mental illness, early detection, early treatment, early intervention is very critical. Depression of the early manifestations of the main emotional anomalies, behavioral changes, personality changes, as follows: 1, emotional anomalies are mainly manifested in a relatively low mood, expression of pain, always sighing, sad, unhappy, unwilling to socialize with others and even with friends, loved ones have no emotional exchanges, so it will appear to be more indifferent, distant, do not care about themselves, do not care about others. 2, behavioral manifestations is mainly a reversal of the previous optimistic and cheerful character traits, become silent, slow, expressionless, always reluctant to go out, lying down less mobile and even some of them become reluctant to participate in the work, and also reluctant to participate in interpersonal activities and even their own daily life do not pay attention to hygiene, become dirty. 3, personality change is mainly from the extrovert to become introvert, used to love to talk and laugh, now become silent, sad and even become more temper, very small things will be easy to get angry and even think that the surrounding friends, family, classmates are always with the patient, because of trivial things and parents, family, friends quarrel, if there has been such a symptom response or even more abnormal self-harming behaviors, suicidal behavior, it is best to consult a doctor and treatment. It is best to seek timely medical attention and treatment.