The reasons for itching on both sides of the vulvar lips at night during pregnancy may be related to secretion stimulation, vulvovaginitis, vaginitis, etc., which can be relieved by local cleansing and the use of medication. 1. Secretion stimulation: during pregnancy, women will be due to the fluctuation of hormone levels in the body and increased secretions, especially on the vulvar area to produce stimulation and itching symptoms, you can pay more attention to the perineal area of the clean, you need to use warm water to wash, is conducive to the removal of secretions, but also to relieve the phenomenon of itching. 2. Vulvovaginitis: itching on both sides of the vulvar lips during pregnancy, you can also follow the doctor’s instructions to choose potassium permanganate sitz bath, can relieve the local itching phenomenon. Not only that, if necessary, you can also choose metronidazole suppository medication to improve the symptoms of vulvovaginitis. 3. Vaginitis: bacterial and trichomonas vaginitis, the use of metronidazole is certainly effective, but this drug is contraindicated in pregnancy, you need to weigh the pros and cons of the use. If and fungal infections, you can also choose to use clotrimazole suppositories medication as prescribed by the doctor. Daily life, it is recommended that pregnant women usually pay more attention to the cleanliness of intimate apparel, daily replacement of underwear, there is a certain role in the prevention of disease. It is recommended to go to the dermatology department of the hospital in a timely manner to clarify the cause of the disease in the doctor’s guidance, symptomatic treatment, do not use their own medication.