Glioma is a common primary malignant tumor in the brain, and its treatment is a comprehensive treatment mainly based on surgery, which means that surgical resection of glioma is undoubtedly very important, but surgical resection is not the whole treatment of glioma, after surgical resection, glioma often needs to be supplemented with radiotherapy and other comprehensive treatments to achieve the best tumor control effect. However, radiotherapy has certain toxic side effects, and many people are worried about the side effects of radiotherapy and whether patients can tolerate it. The main purpose of radiotherapy is to kill the remaining glioma cells and delay the recurrence of the tumor, but not all gliomas need radiotherapy after surgery. Gliomas are classified as high or low grade. According to WHO classification, grade II and I gliomas are low grade gliomas, while grade III and IV gliomas are high grade gliomas. For high-grade glioma, because of high malignancy, fast growth rate and infiltrative growth, radiotherapy is usually needed to control the growth rate and delay the recurrence of the tumor after surgical resection. Therefore, radiation therapy is needed to achieve the goal of increasing tumor control after surgery for high-grade glioma. However, for low-grade glioma, the growth rate of the tumor itself is relatively slow, and whether radiotherapy is needed after glioma resection should be treated differently. Generally speaking, for low-grade gliomas with clear borders, if the tumor has been completely excised and the pathology of the tumor is slow-growing, radiotherapy may not be needed for the time being. However, for low-grade glioma with high-risk factors, such as patient’s age over 40 years old, astrocytoma type, tumor residual, tumor diameter over 6 cm, tumor crossing the midline, neurological deficiency before surgery, etc., further radiotherapy is needed after surgery, etc. If there are no obvious high-risk factors or less than 3 high-risk factors, and the tumor changes slowly, radiotherapy can be temporarily dispensed with. If there are no obvious risk factors or less than 3 high-risk factors, the tumor is generally changing slowly, radiotherapy can be temporarily not needed, but take the way of close observation. And for some patients with poor general condition, such as severe neurological impairment after surgery and unable to cooperate with radiotherapy, radiotherapy can be suspended. Or if the patient is in poor physical condition and cannot tolerate radiotherapy, radiotherapy can also be withheld. Most gliomas are malignant tumors, so after surgical microdissection, most gliomas require radiotherapy or concurrent radiotherapy. However, for gliomas without significant risk factors or if the patient is in poor general condition and is estimated to be unable to tolerate radiotherapy, radiotherapy can be withheld and other adjuvant therapies such as drugs can be used to control the growth of gliomas.