The criteria for stopping the medication for hepatitis B patients who are clinically treated with nucleoside analogues are as follows: 1. If you are a major triple-positive patient before taking the medication, you can consider stopping the medication only after the hepatitis B viral DNA turns negative and the hepatitis B e antigen turns negative and the hepatitis B e antibody appears, which should last up to 3 years and the total course of medication should be more than 3 years. 2. The first thing you need to do is to take your medication and stop taking it. 3. If you are a cirrhotic patient before taking the medication, you can’t stop taking the medication, no matter if you are a major or minor triplet.