The physical examination mainly includes the monitoring of vital signs, such as blood pressure, body temperature, heart rate, pulse monitoring, and possibly blood tests, liver function, kidney function, ion, blood sugar, urine routine, which will not be affected by taking sleeping pills. The blood collection during the physical examination requires patients to fast for more than eight hours, while sleeping pills are taken at bedtime, usually about half an hour before bedtime, so it will not affect the patient’s physical examination. However, if patients take sleeping pills for a long time, it may lead to a certain dependence, and there may be a part of the drug will affect the patient’s liver and kidney function. The physical examination in this case can reveal the problem, such as taking sleeping pills that cause the patient’s liver function to be impaired, and this result must be reduced the dose of sleeping pills or adjusted to other sleeping pills.