Spironolactone belongs to a kind of diuretics, belonging to the potassium-preserving class of diuretics. Spironolactone called androstenol has the effect of diuretic swelling, can act in congestive heart failure various factors lead to renal insufficiency triggered by sodium and water retention or due to endocrine metabolism disorders caused by water and sodium retention caused by hypertension, can be applied to spironolactone line of diuretics to treat. Spironolactone mainly acts in the renal distal tubule, has the effect of interfering with aldosterone metabolism, can make the potassium ion absorption increase, at the same time has the effect of sodium diuresis. However, the diuretic effect of spironolactone is not as good as that of hydrochlorothiazide or furosemide. In addition, spironolactone can act directly on the distal tubule of the kidney, although this drug has the effect of preserving potassium, but the application of blood ion concentration should be regularly monitored.