The rational use of antiepileptic drugs is the main means of current treatment for children with epilepsy, and the specific medication choices are as follows: 1. For generalized seizures or unknown classification, it is recommended to use broad-spectrum antiepileptic drugs, such as valproic acid, topiramate, lamotrigine, levetiracetam, zonisamide, clonazepam, etc.; 2. For focal seizures or idiopathic generalized tonic-clonic seizures, narrow-spectrum antiepileptic drugs, such as carbamazepine, oxcarbazepine, and phenytoin sodium; 3. For infantile spasms or epileptic encephalopathy, special medications such as adrenocorticotropic releasing hormone and aminoglutethimide can be used. Although drug therapy can better control the condition of children with epilepsy, there are also certain adverse effects. For example, for children with myoclonic, akathisia and atonic seizures, it is important to note that carbamazepine, oxcarbazepine, phenytoin sodium, and high doses of phenobarbital can induce or aggravate myoclonic, akathisia and atonic seizures when selecting medications. If the child is allergic, be aware that drugs such as lamotrigine, carbamazepine, oxcarbazepine, and phenytoin sodium can lead to allergic skin mucosal injury, at which point the appropriate drug should be selected for treatment. In addition, it is important to note that when phenytoin sodium is applied, it can lead to adverse reactions such as hypertrichosis, tremor, gingival hyperplasia and ataxia in children. If any of these adverse reactions occur, it is recommended to promptly seek medical advice to adjust the medication regimen.