Post-ovulatory toothache does not have any relationship with pregnancy, not to mention that it does not mean that the patient will definitely get pregnant. If the patient is pregnant after ovulation, the blood chorionic gonadotropin, progesterone and estrogen levels will increase, and the patient’s clinical reactions may include nausea, vomiting, fatigue, drowsiness, breast swelling, breast enlargement, areola deepening, areola enlargement, easy erection of nipples, or the patient may be accompanied by nipple breast milk overflow, and deepening of the color of the vulva and areola of the breasts, etc. The patient’s toothache after ovulation does not have any relationship with pregnancy, and it should be considered that it may be caused by local inflammation of the mouth or other problems. Toothache after ovulation is not related to pregnancy and may be caused by localized inflammation of the mouth or other problems. However, if the patient did not use contraception during ovulation, or if the patient intends to become pregnant, the toothache after ovulation should be treated with medication. Because many medications, such as tinidazole, ornidazole, or ofloxacin, cannot be used during pregnancy, try to choose medications that can be used during pregnancy.