Rabies vaccination does not require a skin test. The drugs that require a skin test are mainly penicillin antibiotics or cephalosporin antibiotics. In clinical practice, there may be other drugs that require skin testing, but it is mainly done when the possibility of allergy is considered more likely. The rabies vaccine is relatively safe and, like most other vaccines, does not require a skin test prior to injection. For rabies vaccination, the main injection is given intramuscularly in the deltoid muscle of the upper arm, and when injecting, you need to know how many shots you should give. If it is pre-exposure prophylaxis, three injections are required. For post-exposure prophylaxis, you can use either the five-shot method or the four-shot method. In the case of the four-stitch method, two injections are needed for the first time, one in the deltoid muscle of the left and right upper arms.