The antihypertensive drugs of Puli class belong to angiotensin-converting enzyme inhibitors, and their representative drugs are captopril, enalapril, benazepril, fosinopril and so on. Angiotensin-converting enzyme inhibitors inhibit circulating and tissue angiotensin-converting enzyme to reduce the generation of angiotensin II, and also inhibit the kinase enzyme to reduce the degradation of bradykinin, which can lower blood pressure and play a role in lowering blood pressure. Angiotensin-converting enzyme inhibitors can also improve insulin resistance and reduce proteinuria, and have inhibited the role of myocardial remodeling, in the clinic is widely used in hypertension, chronic heart failure, coronary heart disease, hypertension with diabetic nephropathy treatment. Adverse reactions are mainly irritating dry cough and angioedema, for women with hyperkalemia, pregnancy, and bilateral renal artery stenosis patients should be prohibited.