In the outpatient clinic received a lot of brain damage caused by kernicterus jaundice, jaundice if controlled in time, there would not be sequelae, but some parents are negligent, thinking that it is normal for babies to have jaundice, as a result, delayed treatment, and triggered brain damage. After brain injury, it takes several years of recovery, which is a huge burden on the family, so parents should pay attention to newborn jaundice. 1, why is neonatal jaundice a time bomb around Newborn jaundice is a common symptom of newborns and is often encountered by parents, but parents seldom know what is the harm of neonatal jaundice and why it is necessary to intervene. This is because neonatal jaundice can lead to kernel jaundice if not intervened in time, and what kind of disease is kernel jaundice? Kernicterus is actually severe neonatal jaundice, also known as “bilirubin encephalopathy”. When neonatal jaundice reaches a certain level, bilirubin crosses the blood vessel wall and enters the brain tissue to stain the nuclei of central nerve cells yellow, so it is called “kernel jaundice”. After the nerve cells are stained by it, they can not carry out energy metabolism, so degeneration and necrosis will occur, and irreversible damage will be formed. The damage of kernel jaundice is permanent, and will accompany the child for the rest of his life. Kernel jaundice is easy to leave behind sequelae such as mental retardation, tetany, hearing impairment, convulsions and so on, and the prevention of this disease is the key. The auditory channels of the brainstem are very sensitive to the toxic effects of bilirubin and are prone to deafness and severe auditory neuropathy, which does not necessarily lead to hearing loss and may be manifested as difficulty in understanding speech in noisy environments. The main manifestations of tetany are involuntary, purposeless, uncoordinated movements of the limbs, aggravated by nervousness, and so on. 3.Kernel jaundice is a preventable disease and should not be a problem in the 21st century. There is no specific treatment for neonatal jaundice, and because neonatal jaundice is very common, it is easy to be ignored by parents and many jaundiced babies are brought to the hospital only when they have developed kernel jaundice, which, unbeknownst to them, has caused neurological damage to babies, thus leaving sequelae such as loss of hearing and intellectual developmental disorders, and bringing a heavy burden on the society and the family. This will bring a heavy burden to the society and the family. Timely hospitalization is the key to preventing and treating kernicterus jaundice, so early screening and early intervention of neonatal jaundice is particularly important. Kernicterus jaundice is not uncommon in our country, at least tens of thousands of cases every year. Such a serious disease should be rare in everyone’s impression, so what is the actual situation? In Europe and the United States and other developed countries, the incidence rate of 1.5/10 million. As China has not yet established a nuclear jaundice registration and reporting system, the lack of demographic-based flow survey data, only in 2009, the Chinese Medical Association organized a flow survey of 33 hospitals, the hospitals surveyed reported a total of 348 cases of bilirubin encephalopathy in newborns, accounting for about 4.8% of the total number of children admitted to the hospital, which can be deduced that the country each year, at least up to tens of thousands of cases. The children’s monthly rehabilitation costs, ranging from a few thousand to tens of thousands of dollars, bring not only economic pressure on the family, but also more spiritual despair. 5, always observe the performance of the baby, find timely medical treatment Nuclear jaundice progresses faster within 24 hours, and there are different clinical manifestations at different stages: Here to remind parents, the newborn within 4-10 days after birth must closely observe the progress of jaundice, and test the blood bilirubin concentration at any time. Jaundice can be closely observed daily by placing the newborn baby in front of a window under natural light. Press the forehead, chest and hearts of hands and feet with your hand for 1-2 seconds, then release your hand and observe the yellowing of the skin. Once yellowing of the white eyes, yellowing of the diaper stain and yellowing of the tears are detected, immediate medical attention should be sought for early intervention and treatment. Special attention should be paid to the baby’s jaundice does not subside, or even deepen and aggravate or recur after subsiding, etc. We should be alert to the possibility of nuclear jaundice. Neonatal jaundice intervention is to prevent the emergence of severe jaundice and kernel jaundice, which is the responsibility of parents, doctors and the whole society, and the responsibility of parents is the most important!