Ventilatory lung dysfunction is a disorder of pulmonary ventilation, and severe pulmonary ventilation dysfunction is a more serious condition. Pulmonary dysfunction is caused by a variety of lung diseases that adversely affect the ventilation of the lungs, and the disease itself can lead to respiratory symptoms such as dyspnea, chest tightness, and shortness of breath. The development of severe pulmonary ventilation dysfunction will lead to the accumulation of carbon dioxide in the body’s blood, causing hypoxia, which will ultimately lead to respiratory failure and jeopardize the patient’s life. In conclusion, severe pulmonary dysfunction is a serious condition, and patients must cooperate with their doctors to improve oxygen saturation. Individuals who always have unexplained dyspnea in their daily life should seek medical treatment as early as possible, improve the examination, clarify the cause and diagnosis, and standardize the treatment under the guidance of professional physicians.