Most of the sleeplessness is due to physiological reasons or pathological reasons, may not be purely which organs have problems, the treatment should be aimed at the specific causes to regulate. 1. Physiological reasons: most of them are caused by psychological factors, environmental factors, drugs and other reasons, such as patients with chronic overwork, stay up late to work overtime, often drinking coffee and tea or taking analgesics, etc., may lead to the phenomenon of sleeplessness, it is recommended that timely adjustment can alleviate the state of poor sleep. 2. Pathological reasons: such as anxiety, depression, cerebral blood supply insufficiency and so on. (1) Anxiety: the spirit of long-term anxiety and fear state, will prompt the brain nerve is in a state of excitement, thus leading to sleep difficulties. (2) Depression: patients will be depressed and not interested in anything, which will put the nerves in a state of tension leading to sleep disorders. (3) Insufficient blood supply to the brain: it will affect the blood supply to the brain tissues, leaving the brain tissues in a state of hypoxia and affecting the quality of sleep. The phenomenon of not being able to sleep, it is recommended that we should consult a doctor in time to find out the cause of the problem, and regulate and treat the cause of the problem, so as not to delay too long, and avoid affecting the health of the body.