The inability to stand up from squatting may be caused by physiological reasons such as overwork, trauma, knee diseases and lumbar spine diseases and other pathological reasons. 1. Physiological reasons: such as overwork caused by the accumulation of lactic acid in the leg muscles, weakness, the patient may appear squatting down and can not stand up symptoms. 2. Trauma: due to trauma and other violent factors lead to lower limb bones, meniscus, ligaments, muscles and other soft tissue injuries, squatting involves the damaged tissues, the patient can not stand up. 3. Knee diseases: such as osteoarthritis, rheumatoid arthritis, rheumatoid arthritis and other diseases, patients can squat and can not stand up. 4. Lumbar spine diseases: such as lumbar disc herniation, lumbar spine slipped and other diseases, compression of the nerves innervating the lower limbs, the patient appears to have lower limb weakness, so the patient can appear squatting and can not stand up. Squatting can not stand up may also have other reasons, it is recommended to go to the hospital in a timely manner, improve the examination to clarify the cause of the disease, give targeted treatment and treatment.