Infants with rashes around the mouth to consider the possibility of hand, foot and mouth disease, eczema, etc., can take general treatment and drug treatment. 1. Hand, foot and mouth disease: hand, foot and mouth disease can appear around the mouth rash, at first for the hemorrhagic spots like a small rash, gradually turned into herpes. The main symptomatic treatment is mainly taken, and the generalized itching of the skin can be used externally with glycerite. If neurological symptoms such as cervical obstruction, convulsions and seizures, mental depression, etc. need to be alert to the possibility of severe hand, foot and mouth, need to be hospitalized in a timely manner, in accordance with the doctor’s orders to be mannitol to reduce intracranial pressure and other treatments. 2. Eczema: the core of eczema is moisturizing, itching can be serious under the guidance of a doctor to apply dinexed cream and other medication. The baby’s mouth rash, there are other causes, such as immune thrombocytopenia, etc., it is recommended to go to the hospital in a timely manner, improve the examination to clarify the cause of the disease, to give targeted treatment or treatment. All of the above medications should be used under the guidance of a doctor.