Splenomegaly refers to the enlargement of the spleen volume and is an important pathological sign of spleen disease. Under normal circumstances, the spleen cannot be felt in the abdomen, but if the edge of the spleen can be felt in the supine or lateral position, it can be recognized as splenomegaly. The degree of splenomegaly can be classified as mild splenomegaly, moderate splenomegaly, and extreme splenomegaly. There are many clinical causes of splenomegaly, such as schistosomiasis, chronic hepatitis, typhoid fever, malaria, portal hypertension, leukemia, malignant lymphoma, etc. Splenomegaly can cause hypersplenism, which reduces blood cells and platelets in the blood. Of course, mild enlargement of the spleen can also be seen in normal people.