Total cholesterol of 7.80 mmol/L may be more serious. The normal range of serum total cholesterol should be less than 5.20 mmol/L. Therefore, total cholesterol of 7.80 mmol/L is above the upper limit of the normal range, which is considered to be high total cholesterol and may increase the risk of cardiovascular diseases. Changes in total cholesterol levels are closely related to the occurrence and development of cardiovascular diseases, and most of it exists in the blood in the form of LDL cholesterol. LDL cholesterol is easily oxidized into the vascular lining to participate in the formation of atherosclerotic plaques. Therefore, high levels of total cholesterol can lead to the development of atherosclerotic cardiovascular diseases and increase the risk of coronary heart disease, cerebral infarction and other diseases in patients. Total cholesterol of 7.80mmol/L should be intervened in time, and relevant lipid regulating drugs, such as simvastatin and atorvastatin, should be taken in accordance with doctor’s prescription while adjusting lifestyle. Therefore, if total cholesterol of 7.80mmol/L is detected, the patient should go to the hospital in time and under the guidance of the doctor for regular treatment.