Excessive masturbation for men may affect fertility, mainly reflected in excessive masturbation will cause erectile dysfunction, ejaculatory dysfunction, and will cause urinary system inflammation; excessive masturbation for women is mainly caused by uterine and tubal infections, which will affect fertility in serious cases. If excessive masturbation causes erectile dysfunction and ejaculatory dysfunction in men, then the sperm of men and the egg of women can not be combined successfully, thus failing to form a fertilized egg, which will lead to infertility. Male masturbation may induce aseptic inflammation, such as aseptic prostatitis, this time will be accompanied by urinary urgency and painful urination, if not timely treatment, the patient’s sex life will be greatly affected. Excessive masturbation is more likely to cause urethritis combined with vaginitis, and even upstream infection to the uterus and its annexes, tubulitis, pelvic inflammatory disease caused by blockage of the fallopian tubes, the egg can not be discharged and then and sperm combined will cause infertility. Therefore, it is recommended that patients should scientifically control the frequency of masturbation, and pay attention to personal hygiene, once the symptoms of infertility should be timely to the regular hospital consultation and treatment.